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货号FP-435

ETV6/JAK2融合基因探针试剂(荧光原位杂交法)

货期:
1个月
探针组分:
ETV6/JAK2融合探针
注册证号:
/
应用癌种:

探针设计

ETV6全长橘红色探针;JAK2全长绿色探针

临床意义

  • 其他血液肿瘤
ETV6-JAK2融合基因与多种血液系统恶性肿瘤相关,包括 B-ALL、T-ALL、CML、MDS等 。在儿童早期 pre-B-ALL和成人aCML中均观察到该融合基因。

参考文献

The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia. Blood. 2016;127(20):2391-2405
World Health Organization-defined eosinophilic disorders:2019 update on diagnosis, risk stratification, and management. Am J Hematol. 2019;94:1149–1166
NCCN Guidelines Version 2.2022 Myeloid/Lymphoid Neoplasms with Eosinophilia and Tyrosine Kinase Fusion Genes
Cancer Genetics 243 (2020) 52–72
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